Businesses for Sale in South Carolina

Key Investment Highlights • Established, physician-led outpatient medical practice with more than 25 years of continuous operation in the Charleston market. • Diversified, integrated service platform including primary care, chronic pain management, Physical Therapy, Acupuncture, Massage therapy, and Medication-Assisted Treatment (MAT) • Consistent annual revenue base of approximately $1.7M+ supported by recurring patient volume • Fully equipped 7,500+ square foot facility with favorable occupancy terms available to incoming ownership. • Diversified payer mix including commercial, governme

This modern, family-owned Italian restaurant and pizzeria is the only pizza shop in the area, making it a popular local favorite with steady year-round demand. Operating successfully for five years, the business offers authentic Italian dishes, high-quality pizza, and a welcoming atmosphere that keeps customers returning in a rural market with limited dining options. Best option would be for an owner operator. With its strong reputation, loyal customer base, and prime location, the restaurant is perfectly positioned for growth. Opportunities include expanding hours, adding delivery, catering

You want to take advantage of this opportunity to acquire an established neighborhood wine and spirits retailer serving the Upstate South Carolina market. Your $200,000 purchase price INCLUDES $150,000 Inventory. Start with over $400K of recurring revenue. Uniquely located within an established residential area, this business has built a 10 year loyal local following by delivering the fundamentals customers want from their neighborhood liquor store: convenience, competitive pricing, reliable inventory and exceptional personal service. Customers consistently compliment the business for its cle

This residential garage door service business offers a rare opportunity to acquire an established home services company in the growing Midlands region of South Carolina. Backed by a nationally recognized franchise brand, the company provides garage door repair, replacement, installation, opener services, emergency repairs, and preventative maintenance to a large and expanding customer base. One of the business's most valuable assets is its exceptional reputation in the marketplace, reflected by over 800 five-star Google reviews. This level of customer validation is difficult to replicate and

NOTE: BUY OUT ONE OF THE PARTNERS NOW AND THE OTHER WILL STAY ON TO ENSURE A HIGH RETENTION RATE OF THE EXISTING CUSTOMER BASE. IN 2-3 YEARS THE BUSINESS WILL BE ELIGIBLE FOR SBA FINANCING AND YOU CAN BUY OUT THE SECOND PARTNER! A father and son partnership has successfully built this highly profitable business. Father paints and son creates amazing finishes to patios, driveways, basements, garages and any place that needs weather-proofing and beautifying. The sale comes with well trained crews of Independent Contractors, a fleet of vehicles and more.  Without almost no marketing, the busine

Deal Structure: $250,000 includes Liquor Inventory of $300,000 and $100,000 in Liquor Store Shelving, Keg Beer Dispenser, Bar Structure, Delivery Truck, Decor, etc. This Opportunity is for Current Store Owners or Individuals who would like to start a Liquor Business at a Lower Cost. The Seller is a Tenured Liquor Store and Beer/Wine Store Owner who knows what Products customers want.  The Owner needs to Liquidate and is motivated.  The sale does not include a leased space and the Inventory will need to be moved by the Buyer.  More Information including Full Inventory List is availa

************NOT SBA ELIGIBLE / CASH HEAVY / ALL NUMBERS CAN BE PROVED********** This represents a rare opportunity to acquire a highly profitable, full-service floral retailer and design studio located in the desirable Lower Grand Strand Area of South Carolina. Established over 50 years ago, it’s a true pillar of the local commercial landscape. The firm is recognized for its commitment to 100% Florist-Designed and Hand-Delivered arrangements, ensuring superior quality control and exceptional customer satisfaction. This offering presents a stable, turn-key operation with significant growth po

Step into ownership of an elegantly established ladies’ clothing boutique generating over $750,000 in annual revenue with $150,000 in profit. The curated, ready-to-sell inventory is additional @ +-$70,000. This boutique has been meticulously built and operates seamlessly with experienced, dependable staff overseeing daily operations—offering a highly attractive semi-absentee ownership profile. Ideally positioned within a vibrant shopping center anchored by a nationally recognized retailer, the boutique benefits from consistent foot traffic, ample parking, and a complementary mix of sought-aft

One of a kind Italian market that offers fresh pasta, heat and eat prepared foods, ravioli, deli sandwiches, imported Italian delicacies.  Perfect business for a working couple or partnership, similar to how the sellers run it.  Perfectly located in a area where the locals appreciate the finer things in life, this a well-established Italian fresh pasta market and located in the Eastern Coastal region of South Carolina is known for its high quality product and has quickly become a local favorite. The business has built a loyal client base and a strong reputation for authentic Italian offe

Own this Incredible Cycling Studio with Top of the Line Equipment, Growing Community of Members, and Unbeatable Location! Since 2023, this Business has been building a Community of Loyal Members who want to be a part of something Big. Nestled in one of America's top College Towns, this Business has become a staple of Fitness in the area. If you are looking for an Easy Entry into the Fitness Industry, A Popular Location in a Top College Town, and The Opportunity to Grow a Community of Devoted Fitness Patrons, this is your Opportunity! The Build-out on the Location has resulted in extremely

Successful Magazine & Digital Marketing Firm– Charleston County, SC This is a unique opportunity to acquire a respected and long-running print and digital media company located in one of Charleston County’s most vibrant and fast-growing markets. With decades of brand recognition and strong advertiser loyalty, this business is well-positioned for continued success and expansion. The company publishes a high-quality regional magazine and offers a full suite of digital marketing services. Known for its connection to the local community and its ability to deliver results for advertisers, the bus

Are you looking to invest in a thriving construction business with a proven track record of success? Look no further than this established Construction Garage Doors business located in the Upstate Region of SC. With two years of experience in the industry, this business is now on the market, presenting a lucrative opportunity for potential buyers like you. This Construction Garage Doors business has built a solid reputation for delivering high-quality services and products to a loyal customer base. The business boasts a strong presence in the local market, serving both residential and commerci

Med spa in the carolinas recently remodeled. Complete modernized med spa set up with Cool sculpting, Msculpt, Restilene, Juviderm, Botox, Hair removal, Hair restoration, Laser wrinkle removal, Micro needling Aesthetic solutions for everyone Ready for expansion https://tworld.com/locations/South-Carolina/coastalsc/listings/Med-Spa-near-The-Coast-in-The-Carolinas

Price is now at $295,000 but will take offers. Recent price changes due to owner adding more vehicles and equipment like vacuums, Batteries and work trucks to meet demand. Business makes more profits in the future in a myriad of ways such as keeping the same monthly prices year round, selling parts, motors, pumps hurricane season and draining over flowing pools. Big profits on chemicals and repairs so they have a large amount of routes to broaden their client base. Owner is tired of the business. Willing to give it up to a new owner. This wont last long. Exciting opportunity to acquire a well

Well-established Italian Restaurant located in Upstate South Carolina. This is a Hand-On Business for an Owner who likes to cook Pizza and Pasta! With a small intimate staff, the overhead is low and the Profits are high! With roughly 4 years at the current location, this restaurant is a prime opportunity waiting for the right buyer. Situated on a bustling street in a rapidly growing town, this restaurant boasts a stellar reputation that draws in loyal customers day in and day out. Operating 6 days a week, this eatery is a beloved staple in the community, known for its authentic Italian cuis

The Asking Price for all routes, including 14 vehicles, is $1,000,000 in outright cash, plus $200,000 in estimated possible vehicle financing, plus $100,000 in seller financing (Total Purchase Price: $1,300,000). FedEx Ground Routes for Sale: Well-established and highly profitable FedEx Ground routes. All routes are contiguous, making load sharing among routes efficient. Each business, which is comprised of multiple routes, comes with (1) truck and (1) experienced driver already in place for each route. Business has seen double digit organic growth since inception. Turnkey and a great opp

This Vape Store will go quickly. If you want it, come and get it. The Vape Industry is extremely Popular and is showing no signs of slowing down. This store is located in a Busy Charleston Area and includes nearly $200,000 in Inventory. With only about two years of Business history, the store has not yet hit it's peak, and the owner believes it could surpass $1,000,000 in sales per year, not uncommon for these types of businesses.  If you want a Business that is On the Rise, Strategically Located, and in a very Popular Industry, this is your opportunity. The Products are popular and Loca

Deal Structure - Price is $900,000 including $450k Inventory. $682,500 Down Payment - Seller note of $367,000 at 8% Interest over 5 Years. Seller Finance available for Qualified Buyers. Personal Guarantee required for Seller Note.  IMPORTANT: This Liquor Store is owned by a company with multiple locations, which allows the seller to purchase inventory at a better price than single-store owners. The best buyer fit will be a buyer with presently operating liquor stores who can put this store under the same LLC.  NOTE: Financial Data is Owner Estimate based on sales and expenses. Take Ad

Deal Structure: Price $6,658,190 including All Inventory and Real Estate. Inventory at Cost Estimated at about $1.35 Million, Real Estate for sale at $4.25 Million.  Are you looking for a lucrative automotive business opportunity in the heart of South Carolina? Look no further than this thriving Auto Salvage business, now available for acquisition. Established in 2019 after being acquired, this business has seen exceptional growth and success in a short period of time. In just a few short years, this Auto Salvage business has proven its potential for profitability and growth. From averaging

This reputable optometry practice has been serving its community for over 40 years with two well-established locations in growing areas. The practice enjoys strong patient demand, booking appointments one month out, with growth historically limited only by the owner’s chosen work schedule. • Location One (2,400 sq ft): o 2 exam lanes, 1 pre-test lane o Open 44 hours/week, doctor present 16 hours/week • Location Two (1,500 sq ft): o 2 exam lanes o Open 36 hours/week, doctor present 10 hours/week Both locations are fully equipped and staffed, and the areas they serve are experiencing steady res

Established wedding cake business producing 400-500 cakes annually with a loyal customer base and strong brand recognition across the Grand Strand. Located on the north end, the bakery offers year-round revenue through custom wedding cakes, specialty cupcakes, and additional bakery items. With steady demand and a proven reputation as a local favorite, the business is primed for growth. Opportunities include expanding delivery through refrigerated trucks and increasing regional reach. A turnkey operation with consistent sales, multiple revenue streams, and significant scalability for a new own

This listing offers the exclusive, protected territory rights for Clozetivity in Coastal South Carolina, one of the fastest growing custom closet and home organization franchise brands in the country. Clozetivity designs and installs custom storage solutions for closets, pantries, garages, home offices, and entertainment centers, using proprietary design software that allows clients to see a finished, tailored design during their very first in-home consultation. The territory is a home-based, low overhead operation. There is no retail storefront, no warehouse, and no large standing inventory

This profitable outdoor power equipment retail and service/repair business is located in the Midlands of South Carolina. This Business is an exclusive Dealer of a premium brand of chainsaws, robotic lawn mowers, commercial power equipment, zero-turn mowers and much much more. The business has served the communities of Orangeburg, Bamberg, Denmark and Barnwell for over 15 years. The Real Estate is available and is valued at $300,000. There are good schools, and lots of outdoor recreational activities including hunting, fishing, boating, and golf. It is a great place to do business and live. Sel

desirable and high-traffic locations. Positioned in the heart of a thriving commercial district, this business benefits from exceptional visibility, strong foot traffic, and an attractive long-term lease that is significantly below current market rates for comparable spaces in the area. The current operation combines a café and specialty grocery concept, generating established revenue with a loyal customer base already in place. For an entrepreneur looking to enter the food and beverage industry, this is a true turnkey opportunity with substantial value in the existing infrastructure alone. F

Are you ready to seize a delectable opportunity in the heart of South Carolina? Look no further than this charming Franchise Donut Shop business that is now up for sale. Nestled in a prime location, this well-established year-old business is a turn key operation.  Current ownership must sell for personal reasons, after only opening a short time ago.  Business is built out and ready for a new owner.  The franchisor will require an onboarding process, a week of training in Pennsylvania, and a franchise transfer fee.  Location has staff in place and a seller ready to assist the smooth transition.

For several decades, this respected business has been the go-to destination for farmers, pet owners, gardeners, and rural property owners. It offers a comprehensive selection of products, including horse, pet, and livestock feed, animal health care supplies, wildlife feed, fencing materials, lawn and garden seed, plants, and fertilizers. The business enjoys a loyal and diverse customer base, built on a reputation for reliable products and outstanding service. Its strategic location and long-standing relationships with suppliers ensure consistent margins and strong repeat sales. With opportunit

This is an excellent opportunity to acquire a fully equipped restaurant through an asset sale. Ideal for entrepreneurs or expanding operators seeking a turnkey location. Seller is motivated. https://tworld.com/locations/South-Carolina/hiltonhead/listings/Turnkey-Restaurant-Asset-Sale

This business provides specialized cleaning, repair, sealing, and restoration services for residential and commercial customers, transforming kitchens, bathrooms, showers, floors, foyers, and more. Several opportunities for continued growth include expansion into the Savannah territory, adding technicians to increase sales volume, pursuing commercial accounts, expanding relationships with property managers, real estate professionals, and contractors, and increasing digital and direct-mail advertising. Greater promotion of premium services could further increase job volume and average custom

The Asking Price for all routes, including 20 vehicles, is $525,000 in outright cash, plus $625,000 in estimated possible vehicle financing, plus $300,000 in seller financing (Total Purchase Price: $1,450,000). FedEx Ground Routes for Sale: Well-established and highly profitable FedEx Ground routes. All routes are contiguous, making load sharing among routes efficient. Each business, which is comprised of multiple routes, comes with (1) truck and (1) experienced driver already in place for each route. Business has seen double digit organic growth since inception. Turnkey and a great oppor

Bring All Offers! Seller Highly Motivated, looking to Relocate ASAP.  Price of $150,000 includes the Inventory. Seller is willing to negotiate the price.  Owner Operated Vape and Tobacco Business on one of the Busiest Roads in Greenville County. Your Business Revenue made $290k in Sales in 2025. You want to be a Business Owner with a Business that actually makes sense, an Owner who can train you, and a Low Entry Point. Your Business has a High Traffic Location! Loyal Client Base! Huge Potential! Monthly Financial Records show that $7000 Net Profit per month is easily achieved for the owne

This is an amazing  opportunity to acquire a well-established, (14 years) fully equipped salon and spa located in one of the fastest-growing markets in the Charleston area. The business has built a loyal customer base, multiple revenue streams, and a proven operating model that offers flexibility for either an owner-operator or a semi-absentee owner. The salon occupies approximately 1,500 square feet with an affordable lease of just $2,000 per month, including CAM, under a year-to-year renewable agreement. The beautifully maintained facility features six styling stations, a dedicated spa trea

This Plumbing Service would be a great buy for addition by acquisition. It is a 25-year established plumbing company serving the Horry Co. SC market since 2001. The business provides residential and commercial plumbing services supported by two experienced plumbers and a husband-and-wife ownership team. Known for dependable service and strong customer relationships, the company benefits from repeat business, referral-driven growth, and consistent market demand.  Add Additional Licensed Technician — Ownership indicated the company has remained consistently busy and occasionally struggles to k

Are you looking to step into the thriving world of beauty and personal care? Look no further - an amazing opportunity awaits you in sunny South Carolina! We are thrilled to present a well-established Beauty/Personal Care Hair Salon business that is now up for grabs. With a prime location in South Carolina, this salon has been catering to a loyal clientele for over a year, establishing a strong reputation for excellence in the local community. The salon boasts a talented team of experienced hairstylists and beauty professionals who are dedicated to providing top-notch services to their clients.

Well-established, owner-operated commercial refrigeration company with a strong reputation for reliability, quality service, and quick response times. Serving Upstate SC for over 15 years, this business enjoys consistent repeat and referral customers. The company provides service, repair, and installation for commercial refrigeration systems, with a focus on restaurants, retail, and small businesses. Highlights: Excellent reputation and long-term customer relationships Steady revenue and profitability Fully equipped service vehicle(s) and tools included Opportunity for growth and expansi

Deal Structure: $150,000, includes an estimated $110,000 in Assets. Owner is willing to familiarize the new owner for Two Weeks.  Are you ready to invest in a Franchise Fitness business in the heart of South Carolina? Look no further! We are excited to present to you an incredible opportunity to acquire a well-established Fitness Gym in South Carolina that is sure to make you break a sweat - in the best way possible. This Fitness Gym business, located in a prime location has been serving its dedicated clientele for over a decade. With a solid reputation for providing top-notch fitness service

This well-established direct-hire recruitment firm specializes in placing professionals and skilled-trades personnel throughout the manufacturing industry. Backed by more than 30 years of recruiting experience, the company has earned a reputation for professional service, efficient execution, timely communication, and high-quality candidate information. As a member of a major national recruiting network, the business benefits from established relationships with recruiters across the country, enabling it to support client searches nationwide. This opportunity is well suited for an experienced r

Deal Structure: Semi Absentee Owner - Full Price Down - Franchisor Approval Required Are you ready to step into a thriving food business in the heart of South Carolina? Look no further than this exceptional Franchise Restaurant Business that's now available for sale! With a prime location and a solid reputation, this is a golden opportunity for aspiring entrepreneurs or seasoned business owners looking to expand their portfolio. This well-established Food Retail Deli Take Out business has been delighting customers for over several years with its delicious menu offerings and exceptional serv

The Asher Theatre and Conference Center is a multifaceted entertainment and event venue located at 3237 Waccamaw Boulevard in Myrtle Beach, South Carolina. Established in 2018 by entertainer James Stephens III, the Asher was created to provide professional, family-friendly entertainment while serving the local community and tourism market. The venue features live theatrical and musical entertainment, including Stephens’ signature Man of a Thousand Voices production and the popular Motown ’59 musical revue. Beyond entertainment, the facility operates as a conference and event center with six

For $389,000, you own this well-established, family-owned tire, alignment, and brake shop that has proudly served its community for over four decades, building a trusted reputation through honest service, dependable workmanship, and a loyal base of repeat customers. With two strategically located service centers, the business benefits from strong regional visibility, convenient customer access, and diversified revenue streams across multiple markets. The company offers tire sales and installation, wheel alignments, and brake repair—services that generate consistent year-round demand and reliab

Presenting an exceptional opportunity to acquire an established non-medical home care franchise. This business specializes in private pay, Medicaid, VA, and long-term care insurance services, catering to a rapidly expanding market in the health, medical, fitness, and beauty sector. With an asking price of just $12,500, this franchise is a scalable venture with nationwide potential, ensuring a promising return on investment. ZERO FRANCHISE FEE!! The franchise offers a turnkey business model, with franchisees receiving full onboarding, lead generation assistance, and operations coaching. The