Gene And Cell Therapy Regulatory Consulting

The Company is a clinical-stage oncology company with a platform that combines biospectral impedance and AI/ML for point-of-care cancer detection. The lead product delivers rapid, in-procedure assessment of surgical margins—identifying the presence and location of cancer within minutes. Initial commercialization targets skin cancer, where the lead product can shorten procedures, spare healthy tissue, improve surgeon economics, and enhance outcomes. The Company has also built a compelling breast cancer dataset and plans to deploy the lead product to help dramatically reduce the ~20–25% re-surgery (re-excision) rate in partial mastectomies; the breast program is in line for non-dilutive CPRIT support. The Company has a collaboration with PHC Holdings (formerly Panasonic Healthcare; TSE:6529) to commercialize the lead product. The company anticipates FDA clearance in 2026 and profitability in 2028. Beyond skin and breast, the Company has generated promising data in lung, pancreatic, esophageal, and colon tissue. Follow-on products include a rapid biopsy-assessment device and a needle-based device leveraging the same platform. Use of Proceeds: This round will fund FDA clearance activities and the initial commercial launch of the lead product. NDA is required to receive comprehensive Confidential Information Memorandum (CIM) crafted by ProNova Partners.

Our client opportunity was developed and founded by two giants of the industry. One of the founders brings a thirty-year career with the New York Football Giants in various director and executive capacities. He founded and chaired the NFL Video Directors Executive Committee, has multi-Emmy winning shows, multiple Telly and Aurora awards, three Super Bowl rings, and was a technical innovator on the team that created instant replay. The other founder was head of programming at Disney Channel for eleven years where the channel won over 100 Emmy/Ace awards and grew profits 20% per year for 10 years. He co-founded Tennis Channel managing launch and operations, and has launched over 30 TV channels including streaming channel Players TV and 18 Short Movie Channels worldwide. Our client has secured distribution agreements with major streaming platforms including Roku, Apple TV, Amazon Fire TV, Samsung TV, Mobile Users (Apple iOS and Android OS), and All Web Applications. Our client currently offers 50 hours of programming to viewers and is available on 500,000,000 devices with active streaming capability. Our client’s opportunity is currently operating. It is an English-language Italian and Italian American focused streaming channel and media brand targeting 30 million Italian Americans and 160 million Italophiles in the U.S. Our client has soft launched as a proof of concept and is building viewership through this ubiquitous distribution platform. Programming inventory consists of 50 hours of current programming featuring original and acquired programs in categories of cooking, Italian American lifestyles, culture, travel, comedy, inspirational, and documentaries. BritBox, a comparable British programming streaming service, recently sold 50% to the BBC for $322 million yielding a $644 million valuation. Our client targets a significantly larger audience of approximately 200 million Italian Americans and Italophiles through AI advertising, sponsorship, and e-commerce integration. The owners have an ecommerce platform in development through which viewers can purchase select Italian exquisite products and services, travel opportunities and other products featured on the channel. NDA required to receive comprehensive Confidential Information Memorandum (CIM) crafted by ProNova Partners.

Our client is an exploding, music talent agency--yearly revenue has increased since inception, at a percentage rate year over year of approximately 600%. Our client is a 'positive hustle and hard work ethic' music talent business built on the sheer effort of bringing music artists to the performance stage. Built from the ground up, the business foundation has been developing emerging performance talent while using well-known artists to kick in larger revenue when possible. A great source of success has come from acquiring visas for in-demand international artists and bringing them to the US marketplace. Our client brings the following: - 80+ acts signed to exclusive contracts (1-to-2-year terms) - Robust artist scouting protocol signing on average 3 acts a week - Can be staffed with agents anywhere in the world - Access to the nation's largest contact book of venues, talent buyers, and promoters - Non-exclusive booking rights for Snoop Dogg, Ice Cube, OT Genasis, Xzibit, Warren G, Bizzy Bone, B.o.B, and Bone Thugs N Harmony - Over 1,000 performances booked in half of a calendar year (2022) - Artists in several genres are actively leaving their current booking agencies in favor of coming onto our client's roster. Our client has been awarded positive recognition by a large majority of its artists as well as publications like MoneyGeek, DMC World, Pollstar, Gigwell, and Shoutout Atlanta. The Company's key paradigm is to find and monetize talent. Our client's team is constantly scouting new talent locally and internationally and bringing them to the marketplace. Our client consults on all aspects of artist growth from graphic design and social media strategy to music guidance and consulting. Urgency drives the foundations and operations of Our client's enterprise. This has proven to be a successful strategy, as month over month, our client is showing exceptional growth: in 2022 up to July, the Company is averaging $86,500 per month in gross revenue. NDA is required to secure a comprehensive Confidential Information Memorandum (CIM) crafted by ProNova Partners. Growth/Expansion: In CIM. Financing: Seller does not wish to finance. Support & Training: Provided at no charge to enable a smooth transition. Reason for Selling: other projects.

The Company operates in the healthcare technology space with a focus on addressing gaps in dementia and Alzheimer’s care. The company has built an ecosystem where data is collected from caregivers and patients in real-time and pushed into physicians’ EHR/EMR systems to monitor the effectiveness of the prescribed treatment plan. Alzheimer’s Disease and other dementia is the first condition that the platform will be focused on. Its platform supports physicians in managing patients through tools that enable remote monitoring and data collection, allowing for more continuous oversight rather than episodic intervention. The business generates revenue through a combination of public healthcare reimbursements and collaborations with pharmaceutical and research entities. Its model emphasizes integrating digital health solutions into clinical workflows to improve patient tracking and care coordination. The Company’s target users include healthcare providers, caregivers, and researchers working with aging populations impacted by cognitive decline. NDA is required to receive comprehensive Confidential Information Memorandum (CIM) crafted by ProNova Partners.

Our client offers a NFT fantasy franchise sports platform, built on blockchain technology, that introduces true in-game ownership of franchises, teams, and players through the use of NFTs (Non-Fungible Tokens). Unique to our client, customers will own their franchise and their players indefinitely, unless they wish to sell, trade, rent, lease, or perform some other smart contracts. Our client's NFTs are made possible and exceptional by confirming ownership, providing secure transactions, and ensuring that no asset can be duplicated. Our client's product strives to mimic real professional leagues as closely as possible. This innovative platform can be used for all sports around the entire planet! The platform is a fantasy franchise sports game confirms the owner of all assets involved: from franchises to active players; all the way down to the lowest prospect. It also confirms each and every activity. Top 10 Features: 1. Create an account. 2. Once a user has an account, they can either create a fantasy franchise league by paying a fee to receive sports teams and their respective players or receive one by transfer or purchase of a team in an existing league. 3. Any user can stake Sports Coin (SPC) on any real or publicly available fantasy franchise sports game to earn SPC based on the staked players or teams' performance. 4. Players can have one place to see all the relevant stats they need to predict games or follow their favorite players. 5. Free text and soon free audio/video calls. 6. History gives the ENTIRE transaction history. 7. Verify identity using BasisID. 8. Trade, transact, or earn SPC from fantasy franchise NFTs 9. Store Bitcoin/Ethereum to buy Score coin 10. Use the Lightning/Raiden Network for instant free transactions Our client's software is 'ready to go;' and is operating with active customers and net income. NDA is required to secure comprehensive Confidential Information Memorandum (CIM) crafted by ProNova Partners. Detailed Information Facilities: N/A Growth & Expansion: Unlimited worldwide. Financing: Sellers will consider, BitCoin preferred Support & Training: As needed specific terms for transition support can be negotiated. The Seller wishes to facilitate a successful and smooth transfer of the Business. Reason for selling: Expansion.

The Company provides IT and telecommunications solutions, specializing in IT security, network infrastructure, software development, enterprise management, and systems support. It delivers global telecommunications through fiber and other networks and offers program management, telecom licensing, and continuity of operations support. Clients are primarily Department of Defense agencies and sub-agencies, with licensed technicians and small business set-aside contracts. The largest contract accounts for 27.0% of year-to-date revenue, with DISA contracts totaling 44.8%. The Company has consistently received “Excellent” ratings in CPARS and operates from leased office space with a secure, government-inspected facility for sensitive document storage. Confidentiality is a concern for the Seller as he seeks just the right buyer, and so the location information provided in the ad is that of the broker, and not of the Business.Business location and name will be shared once a qualified Buyer prospect is vetted. NDA is required to receive comprehensive Confidential Information Memorandum (CIM) crafted by ProNova Partners.

Patented Universal Tumor-Targeting Drug Delivery Platform Co. This pharmaceutical company has developed and patented a universal tumor-targeting drug-delivery platform that can improve the safety and efficacy of many existing chemo treatments, with the ability to target numerous different types of cancer. The technology encapsulates existing FDA-approved drugs inside lipid nanoparticles (liposomes or emulsions) coated with patented human-sourced antinuclear antibodies (ANA). The lipid nanoparticle provides long-term storage stability of the drug and controlled release of the drug over time at body-temperature, and is expected to improve the safety and efficacy profile of the drug, including passive accumulation at the tumor while not harming normal tissues. The Company's ANA, sourced from lupus patients, binds to nuclear material present in abundance in areas of necrosis (dead / ruptured cells) present in and around all solid tumors, thus anchoring the drug-filled nanoparticles at the tumor where the nanoparticle is designed to slowly release the drug directly on the tumor for more effect. As the Company's ANA is not tumor-marker specific, but rather targets necrosis present in solid tumors, the technology is designed to "universally" target many different types of cancer including breast cancer, lung, ovarian, colon, prostate, etc., as well as rare childhood cancers. The Company completed a successful proof-of-concept study at Children's Hospital using Ewing's Sarcoma transplanted in immunodeficient mice. Treatment with the Company's forumlation significantly inhibited tumor growth and extended survival times compared to control mice receiving no treatment or treatment with plain liposomal doxorubicin. The Company has been granted Orphan Drug Designation by the FDA on 2 of the lead drug formulations, providing FDA fee waivers, priority review, and 7-years exclusivity upon market approval. The orphan pathway also enables the potential for New Drug Approval after successful completion of Phase 2 studies, with Phase III data collected while in the market, thus significantly lowering the time and cost to market approval. This same drug inside the Company's tumor targeting delivery system will likely have potential to treat other pediatric cancers, and/or cancers in larger adult populations. As the Company's platform and ANA has the potential to improve the safety and efficacy of many existing FDA approved drugs or even compounds in development, the Company anticipates the potential for multiple licensing agreements with multiple pharmaceutical companies seeking to improve their existing portfolio and extend patient life as they advance into clinical stage. And as it may be possible to file for New Drug Approval following successful Phase II studies, the Company anticipates licensing potential at early clinical stage. Multiple exit opportunities exist with high impact & high ROI. The Company is seeking a supportive capital partner to maintain momentum up to $20M. Funding will be used to advance the lead drug through formal Investigational New Drug enabling studies towards New Drug Approval; estimating $3-5 Million now to advance into clinical studies. Preclinical / animal studies estimate ($3 - 5 Million and 12-18 months); follwed by potential combined Phase I-II clinical study in a rare cancer (approximately 2-3 years and $10M) to potential New Drug Approval, plus additional capital to advance additional drugs in the pipeline simultaneously, thus adding tremendous value to the Company's valuation. Valuations of pharma companies often exceed $100 Million valuation at Phase I (approx. 18 months), and New Drug Approval can exceed valuations above $1 Billion. The Company has numerous, improved high-impact cancer drugs advancing with proper support. NDA is required for comprehensive Confidential Information Memorandum crafted by ProNova Partners. Detailed Information Competition: Trying to improve existing therapies and develop novel approaches to hard to treat cancers. Growth & Expansion: Huge market potential. Financing: If the price and deal structure is right. Support & Training: Transition team included. Reason for Selling: Seeking supportive capital partners to take to the next level(s). .

Our client sources an excellent quality bourbon that has a higher yield than a traditional 6-8-year aged bourbon. Due to the higher yield because of less evaporation, they are able to keep the MSRP very competitive and are growing rapidly. They partner with a smaller craft distillery as their co-packer in order to keep production costs down. The founder is a rising, Tennessee-based singer/songwriter with thousands of followers. He uses, and will continue to use, his social media and concerts to publicize the bourbon and allows fans to become partial minority owners of the brand, thus far garnering approximately $200,000 as of the beginning of December 2022. Since the launch of the bourbon brand in 2018 it has earned some of the largest and most prestigious awards which can be awarded in the spirit industry. 1) Named Top 6 in the World in Forbes 2) Featured in Billboard, Rolling Stone, Uproxx, American Songwriter 3) Platinum Los Angeles 4) Double Gold San Francisco (largest award in the world for whiskey to earn) 5) Double Gold New York International 6) Double Gold New York Best Fifty 7) Gold Las Vegas 8) Silver Denver Our client has created a supportive community of real fans who love both the founder's music and the bourbon. Our client has taken the brand as far as 26 states. They will soon expand into Canada and exporting to South Africa & Vietnam is on the horizon. The founder and his partner are willing to stay on the team to bring the Bourbon brand to a much higher national level with a well-capitalized strategic buyer or owner-operator who is passionate about the bourbon industry. An NDA is required to secure a comprehensive Confidential Information Memorandum (CIM). Growth & Expansion: In CIM - NDA Required. Financing: If the price and deal structure is right Support & Training: Provided at no charge to enable a smooth transition Reason for Selling: Other Projects